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Combination of the Deacetylase Inhibitor Panobinostat and the Multi-Kinase Inhibitor Sorafenib for the Treatment of Metastatic Hepatocellular Carcinoma - Review of the Underlying Molecular Mechanisms and First Case Report

Advanced hepatocellular carcinoma still represents an unmet medical need that has only a limited overall survival despite the introduction of the multi-kinase inhibitor sorafenib. Recently, inhibitors of histone and other protein deacetylases have been established as novel therapeutic approaches to...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Gahr, Susanne, Wissniowski, Till, Zopf, Steffen, Strobel, Deike, Pustowka, Anette, Ocker, Matthias
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Ivyspring International Publisher 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328781/
https://ncbi.nlm.nih.gov/pubmed/22514558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.4211
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