Genetic Variations in TXNRD1 as Potential Predictors of Drug-Induced Liver Injury

PURPOSE: Drug-induced liver injury (DILI) is the most common adverse drug reaction; however, it is not easily predicted. We hypothesize that DILI has a common genetic basis. Based on the findings of previous animal studies on toxic hepatitis, we selected the thioredoxin reductase 1 gene (TXNRD1) as...

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Detalhes bibliográficos
Main Authors: Kwon, Jae-Woo, Shin, Eun-Soon, Lee, Jong-Eun, Kim, Sang-Heon, Kim, Sang-Hoon, Jee, Young-Koo, Kim, Yoon-Keun, Park, Hae-Sim, Min, Kyung-Up, Park, Heung-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328729/
https://ncbi.nlm.nih.gov/pubmed/22548205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2012.4.3.132
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