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SPLENOCYTE APOPTOSIS AND AUTOPHAGY IS MEDIATED BY INTERFERON REGULATORY FACTOR-1 DURING MURINE ENDOTOXEMIA

Sepsis induced lymphocyte and dendritic cell apoptosis contributes to immunosuppression, which results in an inability to eradicate the primary infection as well as a propensity to acquire new, secondary infections. Another cellular process, autophagy, is also activated in immune cells and plays a p...

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Detalhes bibliográficos
Main Authors: Zhang, Lemeng, Cardinal, Jon S, Pan, Pinhua, Rosborough, Brian R., Chang, Ying, Yan, Wei, Huang, Hai, Billiar, Timothy R, Rosengart, Matthew R, Tsung, Allan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328635/
https://ncbi.nlm.nih.gov/pubmed/22266972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318249cfa2
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