Bystander-mediated stimulation of proteolipid protein-specific regulatory T (T(reg)) cells confers protection against experimental autoimmune encephalomyelitis (EAE) via TGF-β

To assess the potency of regulatory T (T(reg)) cells induced against an irrelevant Ag, mice were orally vaccinated with Salmonella expressing E. coli colonization factor antigen I fimbriae. Isolated CD25(+) and CD25(−) CD4(+) T cells were adoptively transferred to naive mice, and T(reg) cells effect...

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Autori principali: Jun, SangMu, Ochoa-Repáraz, Javier, Zlotkowska, Dagmara, Hoyt, Teri, Pascual, David W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328618/
https://ncbi.nlm.nih.gov/pubmed/22418032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2012.02.003
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