Loss of transforming growth factor beta type II receptor increases aggressive tumor behavior and reduces survival in lung adenocarcinoma and squamous cell carcinoma

PURPOSE: Lung adenocarcinoma (AdC) and lung squamous cell carcinoma (SCC) are the most common non-small cell lung cancer (NSCLC) subtypes. This study was designed to determine whether reduced expression of transforming growth factor β type II receptor (TGFβRII) promotes lung AdC and SCC carcinogenes...

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Detalhes bibliográficos
Main Authors: Malkoski, Stephen P., Haeger, Sarah M., Cleaver, Timothy G., Rodriguez, Karen J., Li, Howard, Lu, Shi-Long, Feser, William J., Barón, Anna E., Merrick, Daniel, Lighthall, Jessyka G., Ijichi, Hideaki, Franklin, Wilbur, Wang, Xiao-Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328594/
https://ncbi.nlm.nih.gov/pubmed/22399565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2557
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