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Regulation of Chemokine and Chemokine Receptor Expression by PPARγ in Adipocytes and Macrophages

BACKGROUND: PPARγ plays a key role in adipocyte biology, and Rosiglitazone (Rosi), a thiazolidinedione (TZD)/PPARγ agonist, is a potent insulin-sensitizing agent. Recent evidences demonstrate that adipose tissue inflammation links obesity with insulin resistance and that the insulin-sensitizing effe...

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Bibliographic Details
Main Authors: Nguyen, M. T. Audrey, Chen, Ai, Lu, Wendell J., Fan, WuQiang, Li, Ping-Ping, Oh, Da Young, Patsouris, David
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328487/
https://ncbi.nlm.nih.gov/pubmed/22529965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034976
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