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H(2)S-induced sulfhydration of PTP1B and its role in the endoplasmic reticulum stress response

Although originally considered toxic, hydrogen sulfide (H(2)S) has been implicated in mediating various biological processes. Nevertheless, its cellular targets and mode of action are not well understood. Protein Tyrosine Phosphatases (PTPs), which regulate numerous signal transduction pathways, uti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Krishnan, Navasona, Fu, Cexiong, Pappin, Darryl, Tonks, Nicholas K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328411/
https://ncbi.nlm.nih.gov/pubmed/22169477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002329
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