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Molecular and genealogical evidence for a founder effect in Fanconi anemia families of the Afrikaner population of South Africa
Fanconi anemia (FA) is a rare, genetically heterogeneous autosomal recessive disorder associated with progressive aplastic anemia, congenital abnormalities, and cancer. FA has a very high incidence in the Afrikaner population of South Africa, possibly due to a founder effect. Previously we observed...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The National Academy of Sciences
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33282/ https://ncbi.nlm.nih.gov/pubmed/11344308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091402398 |
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