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Targeting iNKT Cells for the Treatment of Sickle Cell Disease
Sickle cell disease (SCD) causes widely disseminated vaso-occlusive episodes. Building on evidence implicating invariant NKT (iNKT) cells in the pathogenesis of ischemia/reperfusion injury, recent studies demonstrate that blockade of iNKT cell activation in mice with SCD reduces pulmonary inflammati...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328191/ https://ncbi.nlm.nih.gov/pubmed/21429807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2011.03.002 |
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