Sickle Cell Disease (SCD), iNKT Cells, and Regadenoson Infusion

A humanized murine sickle cell–disease (SCD) model (NY1DD) has been used to study ischemia/reperfusion injury (IRI) in sickle cell anemia, and iNKT cells (a very small subset of murine and human T cells) have been found to instigate such injury in this model. Furthermore, levels of activated iNKT ce...

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Autori principali: Nathan, David G., Field, Joshua, Lin, Gene, Neuberg, Donna, Majerus, Elaine, Onyekwere, Onyinye, Keefer, Jeffrey, Okam, Maureen, Ross, Ainsley, Linden, Joel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Clinical and Climatological Association 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540605/
https://ncbi.nlm.nih.gov/pubmed/23303999
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