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Identification of CSPα clients reveals a role in dynamin 1 regulation
Cysteine string protein α (CSPα), a presynaptic co-chaperone for Hsc70, is required for synapse maintenance. Deletion of CSPα leads to neuronal dysfunction, synapse loss, and neurodegeneration. We utilized unbiased, systematic proteomics to identify putative CSPα protein clients. We found 22 such pr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328141/ https://ncbi.nlm.nih.gov/pubmed/22500636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.01.029 |
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