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Cardiac Myosin Binding Protein C Insufficiency Leads to Early Onset of Mechanical Dysfunction

BACKGROUND: Decreased expression of cardiac myosin binding protein C (cMyBPC) as a result of genetic mutations may contribute to the development of hypertrophic cardiomyopathy (HCM); however, the mechanisms that link cMyBPC expression and HCM development, especially contractile dysfunction, remain u...

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Detalhes bibliográficos
Main Authors: Desjardins, Candida L., Chen, Yong, Coulton, Arthur T., Hoit, Brian D., Yu, Xin, Stelzer, Julian E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328136/
https://ncbi.nlm.nih.gov/pubmed/22157650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCIMAGING.111.965772
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