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Metformin attenuates Alzheimer’s disease-like neuropathology in obese, leptin-resistant mice
Diabetes increases the risk of Alzheimer’s disease (AD). The pathological hallmarks for AD brains are extracellular amyloid plaques formed by β-amyloid peptide (Aβ) and intracellular neurofibrillary tangles consisting of hyperphosphorylated tau protein. This study was designed to determine AD-like b...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327803/ https://ncbi.nlm.nih.gov/pubmed/22425595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2012.03.002 |
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