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Consequences of RAS and MAPK activation in the ovary: the good, the bad and the ugly
This review summarizes studies providing evidence 1) that endogenous RAS activation regulates important physiological events during ovulation and luteinization 2) that expression of the mutant, active KRAS(G12D) in granulosa cells in vivo causes abnormal follicle growth arrest leading to premature o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327778/ https://ncbi.nlm.nih.gov/pubmed/22197887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2011.12.005 |
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