Endogenous acetaldehyde toxicity during antral follicular development in the mouse ovary

The biosynthesis of androgens requires multiple steps and during the conversion of pregnenolone to 17α-hydroxypregnenolone and dehydroepiandrosterone (DHEA) by CYP17a1. Acetaldehyde is potentially formed as a by-product in theca cells during antral follicular development. In this study, acetaldehyde...

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Bibliographic Details
Main Authors: Kawai, Tomoko, Mihara, Toshihiro, Kawashima, Ikko, Fujita, Youko, Ikeda, Chiaki, Negishi, Hiroaki, Richards, JoAnne S., Shimada, Masayuki
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327754/
https://ncbi.nlm.nih.gov/pubmed/22285649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2012.01.001
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