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Site-Selective Bromination of Vancomycin

We report the site-selective bromination of vancomycin to produce, with substantial efficiency, previously unknown mono-bromo-vancomycins, a di-bromo-vancomycin and a tri-bromo-vancomycin. We document the inherent reactivity of native vancomycin towards N-bromophthalimide. We then demonstrate signif...

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Bibliografiske detaljer
Main Authors: Pathak, Tejas P., Miller, Scott J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327726/
https://ncbi.nlm.nih.gov/pubmed/22462775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja301566t
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