Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation

Neocentromeres (NCs) are fully functional centromeres that arise ectopically in noncentromeric regions lacking α-satellite DNA. Using telomere-associated chromosome truncation, we have produced a series of minichromosomes (MiCs) from a mardel(10) marker chromosome containing a previously characteriz...

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Hauptverfasser: Saffery, Richard, Wong, Lee H., Irvine, Danielle V., Bateman, Melissa A., Griffiths, Belinda, Cutts, Suzanne M., Cancilla, Michael R., Cendron, Angela C., Stafford, Angela J., Choo, K. H. Andy
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC33277/
https://ncbi.nlm.nih.gov/pubmed/11331754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091468498
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