The 10q25 Neocentromere and its Inactive Progenitor Have Identical Primary Nucleotide Sequence: Further Evidence for Epigenetic Modification

We have previously localized the core centromere protein-binding domain of a 10q25.2-derived neocentromere to an 80-kb genomic region. Detailed analysis has indicated that the 80-kb neocentromere (NC) DNA has a similar overall organization to the corresponding region on a normal chromosome 10 (HC) D...

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Detalhes bibliográficos
Main Authors: Barry, Alyssa E., Bateman, Melissa, Howman, Emily V., Cancilla, Michael R., Tainton, Kellie M., Irvine, Danielle V., Saffery, Richard, Choo, K.H. Andy
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC310875/
https://ncbi.nlm.nih.gov/pubmed/10854414
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