Bim Links ER Stress and Apoptosis in Cells Expressing Mutant SOD1 Associated with Amyotrophic Lateral Sclerosis

Endoplasmic reticulum (ER) stress is an important pathway to cell death in amyotrophic lateral sclerosis (ALS). We previously demonstrated that ER stress is linked to neurotoxicity associated with formation of inclusions of mutant Cu,Zn-superoxide dismutase 1 (SOD1). Cells bearing mutant inclusions...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Soo, Kai Y., Atkin, Julie D., Farg, Manal, Walker, Adam K., Horne, Malcolm K., Nagley, Phillip
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327676/
https://ncbi.nlm.nih.gov/pubmed/22523592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035413
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