Dynamics of Hepatitis B Virus Quasispecies in Association with Nucleos(t)ide Analogue Treatment Determined by Ultra-Deep Sequencing

BACKGROUND AND AIMS: Although the advent of ultra-deep sequencing technology allows for the analysis of heretofore-undetectable minor viral mutants, a limited amount of information is currently available regarding the clinical implications of hepatitis B virus (HBV) genomic heterogeneity. METHODS: T...

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Auteurs principaux: Nishijima, Norihiro, Marusawa, Hiroyuki, Ueda, Yoshihide, Takahashi, Ken, Nasu, Akihiro, Osaki, Yukio, Kou, Tadayuki, Yazumi, Shujiro, Fujiwara, Takeshi, Tsuchiya, Soken, Shimizu, Kazuharu, Uemoto, Shinji, Chiba, Tsutomu
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327662/
https://ncbi.nlm.nih.gov/pubmed/22523569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035052
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