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Achiral Counterion Control of Enantioselectivity in a Brønsted Acid Catalyzed Iodolactonization

Highly enantioselective halolactonizations have been developed using a chiral proton catalyst NIS reagent system in which the Brønsted acid is used at catalyst loadings as low as 1 mol%. An approach that modulates the achiral counterion (equimolar to the neutral chiral ligand proton complex present...

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Detalhes bibliográficos
Main Authors: Dobish, Mark C., Johnston, Jeffrey N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326820/
https://ncbi.nlm.nih.gov/pubmed/22463391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja301858r
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