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Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

Notch proteins function as receptors for membrane-bound ligands (Jagged and Delta-like) to regulate cell-fate determination. We have investigated the role of Notch signaling in embryonic endothelium of the mouse by expressing an activated form of the Notch4 protein in vasculature under the regulatio...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Uyttendaele, H., Ho, J., Rossant, J., Kitajewski, J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2001
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33266/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11344305/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.091584598
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