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Angiotensin-(1-7) Abrogates Mitogen-Stimulated Proliferation of Cardiac Fibroblasts

Previous studies showed that angiotensin-(1-7) [Ang-(1-7)] attenuates cardiac remodeling by reducing both interstitial and perivascular fibrosis. Although a high affinity binding site for Ang-(1-7) was identified on cardiac fibroblasts, the molecular mechanisms activated by the heptapeptide hormone...

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Autors principals: McCollum, LaTronya T., Gallagher, Patricia E., Tallant, E. Ann
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326596/
https://ncbi.nlm.nih.gov/pubmed/22326709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2012.01.020
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