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Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis

INTRODUCTION: CXCL12-CXCR4 signaling has been shown to play a role in breast cancer progression by enhancing tumor growth, angiogenesis, triggering cancer cell invasion in vitro, and guiding cancer cells to their sites of metastasis. However, CXCR7 also binds to CXCL12 and has been recently found to...

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Détails bibliographiques
Auteurs principaux: Hernandez, Lorena, Magalhaes, Marco AO, Coniglio, Salvatore J, Condeelis, John S, Segall, Jeffrey E
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326570/
https://ncbi.nlm.nih.gov/pubmed/22152016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3074
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