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Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis

INTRODUCTION: CXCL12-CXCR4 signaling has been shown to play a role in breast cancer progression by enhancing tumor growth, angiogenesis, triggering cancer cell invasion in vitro, and guiding cancer cells to their sites of metastasis. However, CXCR7 also binds to CXCL12 and has been recently found to...

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Bibliografische gegevens
Hoofdauteurs: Hernandez, Lorena, Magalhaes, Marco AO, Coniglio, Salvatore J, Condeelis, John S, Segall, Jeffrey E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326570/
https://ncbi.nlm.nih.gov/pubmed/22152016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3074
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