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GLI1 orchestrates CXCR4/CXCR7 signaling to enhance migration and metastasis of breast cancer cells

The up-regulation of chemokine receptors CXCR4 and CXCR7 impacts on the distant metastasis and prognosis of breast cancer, though knowledge about the regulatory mechanism of their expressions is limited. Meanwhile, the GLI transcription factors of Hedgehog signaling have been reported to play a pivo...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Inaguma, Shingo, Riku, Miho, Ito, Hideaki, Tsunoda, Takumi, Ikeda, Hiroshi, Kasai, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741792/
https://ncbi.nlm.nih.gov/pubmed/26413813
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