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CHEK2 contribution to hereditary breast cancer in non-BRCA families

BACKGROUND: Mutations in the BRCA1 and BRCA2 genes are responsible for only a part of hereditary breast cancer (HBC). The origins of "non-BRCA" HBC in families may be attributed in part to rare mutations in genes conferring moderate risk, such as CHEK2, which encodes for an upstream regula...

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Main Authors: Desrichard, Alexis, Bidet, Yannick, Uhrhammer, Nancy, Bignon, Yves-Jean
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326561/
https://ncbi.nlm.nih.gov/pubmed/22114986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3062
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