Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER2(+):ERα(−) breast cancer

Human Epidermal Growth Factor Receptor 2-positive (HER2(+)) breast cancer (BC) is a highly aggressive disease commonly treated with chemotherapy and anti-HER2 drugs, including trastuzumab. There is currently no way to predict which HER2(+) BC patients will benefit from these treatments. Previous pro...

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Main Authors: Liu, Jeff C., Voisin, Veronique, Bader, Gary D., Deng, Tao, Pusztai, Lajos, Symmans, William Fraser, Esteva, Francisco J., Egan, Sean E., Zacksenhaus, Eldad
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2012
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326451/
https://ncbi.nlm.nih.gov/pubmed/22460789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201105109
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