Calpastatin Controls Polymicrobial Sepsis by Limiting Procoagulant Microparticle Release

Rationale: Sepsis, a leading cause of death worldwide, involves widespread activation of inflammation, massive activation of coagulation, and lymphocyte apoptosis. Calpains, calcium-activated cysteine proteases, have been shown to increase inflammatory reactions and lymphocyte apoptosis. Moreover, c...

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Detalhes bibliográficos
Main Authors: Zafrani, Lara, Gerotziafas, Grigoris, Byrnes, Colleen, Hu, Xuzhen, Perez, Joelle, Lévi, Charlène, Placier, Sandrine, Letavernier, Emmanuel, Leelahavanichkul, Asada, Haymann, Jean-philippe, Elalamy, Ismail, Miller, Jeffrey L., Star, Robert A., Yuen, Peter S. T., Baud, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326423/
https://ncbi.nlm.nih.gov/pubmed/22268136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201109-1686OC
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