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Bidirectional Relationship between Functional Connectivity and Amyloid-β Deposition in Mouse Brain

Brain region-specific deposition of extracellular amyloid plaques principally composed of aggregated amyloid-β (Aβ) peptide is a pathological signature of Alzheimer's disease (AD). Recent human neuroimaging data suggest that resting-state functional connectivity strength is reduced in patients...

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Hlavní autoři: Bero, Adam W., Bauer, Adam Q., Stewart, Floy R., White, Brian R., Cirrito, John R., Raichle, Marcus E., Culver, Joseph P., Holtzman, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326343/
https://ncbi.nlm.nih.gov/pubmed/22457485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5845-11.2012
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