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Structure of Musashi1 in a complex with target RNA: the role of aromatic stacking interactions
Mammalian Musashi1 (Msi1) is an RNA-binding protein that regulates the translation of target mRNAs, and participates in the maintenance of cell ‘stemness’ and tumorigenesis. Msi1 reportedly binds to the 3′-untranslated region of mRNA of Numb, which encodes Notch inhibitor, and impedes initiation of...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326303/ https://ncbi.nlm.nih.gov/pubmed/22140116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1139 |
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