Disruption of Platelet-derived Chemokine Heteromers Prevents Neutrophil Extravasation in Acute Lung Injury

Rationale: Acute lung injury (ALI) causes high mortality, but its molecular mechanisms and therapeutic options remain ill-defined. Gram-negative bacterial infections are the main cause of ALI, leading to lung neutrophil infiltration, permeability increases, deterioration of gas exchange, and lung da...

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Hlavní autoři: Grommes, Jochen, Alard, Jean-Eric, Drechsler, Maik, Wantha, Sarawuth, Mörgelin, Matthias, Kuebler, Wolfgang M., Jacobs, Michael, von Hundelshausen, Philipp, Markart, Philipp, Wygrecka, Malgorzata, Preissner, Klaus T., Hackeng, Tilman M., Koenen, Rory R., Weber, Christian, Soehnlein, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326286/
https://ncbi.nlm.nih.gov/pubmed/22246174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201108-1533OC
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