Probing Functional Heteromeric Chemokine Protein–Protein Interactions through Conformation‐Assisted Oxime Ligation

Protein–protein interactions (PPIs) govern most processes in living cells. Current drug development strategies are aimed at disrupting or stabilizing PPIs, which require a thorough understanding of PPI mechanisms. Examples of such PPIs are heteromeric chemokine interactions that are potentially invo...

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Foilsithe in:Angew Chem Int Ed Engl
Main Authors: Agten, Stijn M., Koenen, Rory R., Ippel, Hans, Eckardt, Veit, von Hundelshausen, Philipp, Mayo, Kevin H., Weber, Christian, Hackeng, Tilman M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Communications
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132021/
https://ncbi.nlm.nih.gov/pubmed/27785869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201607036
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