Probing Functional Heteromeric Chemokine Protein–Protein Interactions through Conformation‐Assisted Oxime Ligation

Protein–protein interactions (PPIs) govern most processes in living cells. Current drug development strategies are aimed at disrupting or stabilizing PPIs, which require a thorough understanding of PPI mechanisms. Examples of such PPIs are heteromeric chemokine interactions that are potentially invo...

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Detalles Bibliográficos
Publicado en:Angew Chem Int Ed Engl
Main Authors: Agten, Stijn M., Koenen, Rory R., Ippel, Hans, Eckardt, Veit, von Hundelshausen, Philipp, Mayo, Kevin H., Weber, Christian, Hackeng, Tilman M.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
Assuntos:
Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132021/
https://ncbi.nlm.nih.gov/pubmed/27785869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201607036
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