The Role of Innate APOBEC3G and Adaptive AID Immune Responses in HLA-HIV/SIV Immunized SHIV Infected Macaques

The AID/APOBEC family (activation induced deaminase/apolipoprotein B mRNA editing cytokine deaminase) in B cells play important roles in adaptive and innate immunity. Whereas APOBEC3G has been studied in CD4+ T cells and myeloid cells its functional potential in B cells has received little attention...

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Detalhes bibliográficos
Main Authors: Wang, Yufei, Whittall, Trevor, Rahman, Durdana, Bunnik, Evelien M., Vaughan, Robert, Schøller, Jørgen, Bergmeier, Lesley A., Montefiori, David, Singh, Mahavir, Schuitemaker, Hanneke, Lehner, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326050/
https://ncbi.nlm.nih.gov/pubmed/22514633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034433
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