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Gremlin-1 Induces BMP-Independent Tumor Cell Proliferation, Migration, and Invasion
Gremlin-1, a bone morphogenetic protein (BMP) antagonist, is overexpressed in various cancerous tissues but its role in carcinogenesis has not been established. Here, we report that gremlin-1 binds various cancer cell lines and this interaction is inhibited by our newly developed gremlin-1 antibody,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325980/ https://ncbi.nlm.nih.gov/pubmed/22514712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035100 |
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