Gremlin-1 Induces BMP-Independent Tumor Cell Proliferation, Migration, and Invasion

Gremlin-1, a bone morphogenetic protein (BMP) antagonist, is overexpressed in various cancerous tissues but its role in carcinogenesis has not been established. Here, we report that gremlin-1 binds various cancer cell lines and this interaction is inhibited by our newly developed gremlin-1 antibody,...

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Bibliographic Details
Main Authors: Kim, Minsoo, Yoon, Soomin, Lee, Sukmook, Ha, Seon Ah, Kim, Hyun Kee, Kim, Jin Woo, Chung, Junho
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325980/
https://ncbi.nlm.nih.gov/pubmed/22514712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035100
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