Acquisition of Complement Inhibitor Serine Protease Factor I and Its Cofactors C4b-Binding Protein and Factor H by Prevotella intermedia

Infection with the Gram-negative pathogen Prevotella intermedia gives rise to periodontitis and a growing number of studies implies an association of P. intermedia with rheumatoid arthritis. The serine protease Factor I (FI) is the central inhibitor of complement degrading complement components C3b...

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Bibliographic Details
Main Authors: Malm, Sven, Jusko, Monika, Eick, Sigrun, Potempa, Jan, Riesbeck, Kristian, Blom, Anna M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325944/
https://ncbi.nlm.nih.gov/pubmed/22514678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034852
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