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Local Microenvironment Provides Important Cues for Cell Differentiation in Lingual Epithelia
Transgenic Keratin14-rtTA-PTR mice specifically express Keratin14 (K14) in the tongue epithelia, as well as co-express EGFP and the dominant negative ΔTgfbr2 genes upon treatment with Doxycycline (Dox). As TGF-β signaling negatively regulates the stem cell cycle and proliferation, its disruption by...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325925/ https://ncbi.nlm.nih.gov/pubmed/22514735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035362 |
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