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Local Microenvironment Provides Important Cues for Cell Differentiation in Lingual Epithelia

Transgenic Keratin14-rtTA-PTR mice specifically express Keratin14 (K14) in the tongue epithelia, as well as co-express EGFP and the dominant negative ΔTgfbr2 genes upon treatment with Doxycycline (Dox). As TGF-β signaling negatively regulates the stem cell cycle and proliferation, its disruption by...

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Detalhes bibliográficos
Main Authors: Li, Feng, Zhou, Mingliang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325925/
https://ncbi.nlm.nih.gov/pubmed/22514735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035362
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