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Crucial Role of Heme Oxygenase-1 on the Sensitivity of Cholangiocarcinoma Cells to Chemotherapeutic Agents

Cancer cells acquire drug resistance via various mechanisms including enhanced cellular cytoprotective and antioxidant activities. Heme oxygenase-1 (HO-1) is a key enzyme exerting potent cytoprotection, cell proliferation and drug resistance. We aimed to investigate roles of HO-1 in human cholangioc...

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Autors principals: Kongpetch, Sarinya, Kukongviriyapan, Veerapol, Prawan, Auemduan, Senggunprai, Laddawan, Kukongviriyapan, Upa, Buranrat, Benjaporn
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325916/
https://ncbi.nlm.nih.gov/pubmed/22514698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034994
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