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Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair
Signaling pathways depend on regulatory protein-protein interactions; controlling these interactions in cells has important applications for reengineering biological functions. As many regulatory proteins are modular, considerable progress in engineering signaling circuits has been made by recombini...
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| Hoofdauteurs: | , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325720/ https://ncbi.nlm.nih.gov/pubmed/22403064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114487109 |
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