TWIK1, a unique background channel with variable ion selectivity

TWIK1 belongs to the family of background K(+) channels with two pore domains. In native and transfected cells, TWIK1 is detected mainly in recycling endosomes. In principal cells in the kidney, TWIK1 gene inactivation leads to the loss of a nonselective cationic conductance, an unexpected effect th...

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Bibliografske podrobnosti
Main Authors: Chatelain, Franck C., Bichet, Delphine, Douguet, Dominique, Feliciangeli, Sylvain, Bendahhou, Saïd, Reichold, Markus, Warth, Richard, Barhanin, Jacques, Lesage, Florian
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325654/
https://ncbi.nlm.nih.gov/pubmed/22431633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201132109
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