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TWIK1, a unique background channel with variable ion selectivity

TWIK1 belongs to the family of background K(+) channels with two pore domains. In native and transfected cells, TWIK1 is detected mainly in recycling endosomes. In principal cells in the kidney, TWIK1 gene inactivation leads to the loss of a nonselective cationic conductance, an unexpected effect th...

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書誌詳細
主要な著者: Chatelain, Franck C., Bichet, Delphine, Douguet, Dominique, Feliciangeli, Sylvain, Bendahhou, Saïd, Reichold, Markus, Warth, Richard, Barhanin, Jacques, Lesage, Florian
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325654/
https://ncbi.nlm.nih.gov/pubmed/22431633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201132109
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