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TWIK1, a unique background channel with variable ion selectivity
TWIK1 belongs to the family of background K(+) channels with two pore domains. In native and transfected cells, TWIK1 is detected mainly in recycling endosomes. In principal cells in the kidney, TWIK1 gene inactivation leads to the loss of a nonselective cationic conductance, an unexpected effect th...
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主要な著者: | , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
National Academy of Sciences
2012
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325654/ https://ncbi.nlm.nih.gov/pubmed/22431633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201132109 |
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