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TWIK1, a unique background channel with variable ion selectivity
TWIK1 belongs to the family of background K(+) channels with two pore domains. In native and transfected cells, TWIK1 is detected mainly in recycling endosomes. In principal cells in the kidney, TWIK1 gene inactivation leads to the loss of a nonselective cationic conductance, an unexpected effect th...
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Autori principali: | , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
National Academy of Sciences
2012
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325654/ https://ncbi.nlm.nih.gov/pubmed/22431633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201132109 |
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