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TWIK1, a unique background channel with variable ion selectivity

TWIK1 belongs to the family of background K(+) channels with two pore domains. In native and transfected cells, TWIK1 is detected mainly in recycling endosomes. In principal cells in the kidney, TWIK1 gene inactivation leads to the loss of a nonselective cationic conductance, an unexpected effect th...

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Dettagli Bibliografici
Autori principali: Chatelain, Franck C., Bichet, Delphine, Douguet, Dominique, Feliciangeli, Sylvain, Bendahhou, Saïd, Reichold, Markus, Warth, Richard, Barhanin, Jacques, Lesage, Florian
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325654/
https://ncbi.nlm.nih.gov/pubmed/22431633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201132109
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