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Measurement of Altered AβPP Isoform Expression in Frontal Cortex of Patients with Alzheimer’s Disease by Absolute Quantification Real-Time PCR
Enzymatic cleavage of Amyloid-β Protein Precursor (AβPP) produces amyloid-β (Aβ) peptides which form the insoluble cortical plaques characteristic of Alzheimer’s Disease (AD). AβPP is post-transcriptionally processed into three major isoforms with differential cellular and tissue expression patterns...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325610/ https://ncbi.nlm.nih.gov/pubmed/22258516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-111337 |
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