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Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis
The CyclinB1-Cdk1 kinase is the catalytic activity at the heart of Mitosis Promoting Factor (MPF), yet fundamental questions concerning its role in mitosis remained unresolved. It is not known when and how rapidly CyclinB1-Cdk1 is activated in mammalian cells, nor how its activation coordinates the...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325599/ https://ncbi.nlm.nih.gov/pubmed/20412769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.02.013 |
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