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Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis

The CyclinB1-Cdk1 kinase is the catalytic activity at the heart of Mitosis Promoting Factor (MPF), yet fundamental questions concerning its role in mitosis remained unresolved. It is not known when and how rapidly CyclinB1-Cdk1 is activated in mammalian cells, nor how its activation coordinates the...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Gavet, Olivier, Pines, Jonathon
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325599/
https://ncbi.nlm.nih.gov/pubmed/20412769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.02.013
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