Dicer Inactivation Leads to Progressive Functional and Structural Degeneration of the Mouse Retina

MicroRNAs (miRNAs) are small, highly conserved molecules that have been shown to regulate the expression of genes by binding to specific target mRNAs. Dicer, an RNase III endonuclease, is essential for the production and function of mature miRNAs, and removal of Dicer has been shown to disrupt many...

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Main Authors: Damiani, Devid, Alexander, John J., O'Rourke, Jason R., McManus, Mike, Jadhav, Ashutosh P., Cepko, Constance L., Hauswirth, William W., Harfe, Brian D., Strettoi, Enrica
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325486/
https://ncbi.nlm.nih.gov/pubmed/18463241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0828-08.2008
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