A role for solvents in the toxicity of agricultural organophosphorus pesticides

Organophosphorus (OP) insecticide self-poisoning is responsible for about one-quarter of global suicides. Treatment focuses on the fact that OP compounds inhibit acetylcholinesterase (AChE); however, AChE-reactivating drugs do not benefit poisoned humans. We therefore studied the role of solvent cof...

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Detalhes bibliográficos
Main Authors: Eddleston, Michael, Street, Jonathan M., Self, Ian, Thompson, Adrian, King, Tim, Williams, Nicola, Naredo, Gregorio, Dissanayake, Kosala, Yu, Ly-Mee, Worek, Franz, John, Harald, Smith, Sionagh, Thiermann, Horst, Harris, John B., Eddie Clutton, R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325481/
https://ncbi.nlm.nih.gov/pubmed/22365945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2012.02.005
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