BRCA1-IRIS Overexpression Promotes Formation of Aggressive Breast Cancers

INTRODUCTION: Women with HER2(+) or triple negative/basal-like (TN/BL) breast cancers succumb to their cancer rapidly due, in part to acquired Herceptin resistance and lack of TN/BL-targeted therapies. BRCA1-IRIS is a recently discovered, 1399 residue, BRCA1 locus alternative product, which while sh...

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Autors principals: Shimizu, Yoshiko, Luk, Hugh, Horio, David, Miron, Penelope, Griswold, Michael, Iglehart, Dirk, Hernandez, Brenda, Killeen, Jeffrey, ElShamy, Wael M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325250/
https://ncbi.nlm.nih.gov/pubmed/22511931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034102
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